A major advance in the assaying of growth hormone using a new molecule
Improving the daily life of patients suffering from a deficiency in growth hormone
Up until now the assaying of growth hormone required heavy and painful treatments: injections, hospital stays, etc. Invasive methods for the patients.
MacrilenTM, as developed by Æterna Zentaris with the help of the Chemistry of Amino Acids, Heterocycles, Peptides and Proteins team of the Max Mousseron Biomolecules Institute, makes the treatment much simpler for patients. An oral dose of this agonist of the ghrelin receptor provokes the secretion of GH, which can then be dosed with a blood test.
Marketing in the United States set for 2018
The pseudo-peptide compound JMV 1843 discovered by IBMM researchers will be marketed in the United States by Æterna Zentaris during the first trimester of 2018 under the tradename MacrilenTM.
The drug has just received its marketing authorisation (MA) from the FDA for diagnosing a deficiency of growth hormone in adults. It should rapidly find other applications such as in the treatment of growth retardation and cachexia. While awaiting the MA for Europe (which should be received shortly), this project, which begin in 1997 with the company Europeptides (European project Eureka #1923), finally comes to a successful end!